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The study found that all three tea infusions effectively prevented the reduction in urinary NO metabolites, which are indicative of overall NO production, caused by high-salt intake

Green tea polyphenol epigallocatechin-3-gallate (EGCG) induced intermolecular cross-linking of membrane proteins

ROS-Nrf2 pathway mediates the development of TGF-1-induced epithelial-mesenchymal transition through the activation of Notch signaling

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These biotransformation processes by HBMEC may facilitate metabolite elimination from brain or, on the other hand, such modifications may enhance retention or assist further uptake and delivery to other neuronal cell types, therefore spreading their beneficial effects