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NICE stands for National Institute of Health and Care Excellence

Using novel genetic and chemical techniques to fate map pre-made lung ECM in animal models of lung fibrosis, we uncover a novel mechanism of connective tissue proteolysis at PAJs with subsequent mobilization of pleural macromolecules inwards that feeds and sustains pulmonary fibrosis

Peptide therapy works best as part of a broader clinical approach, alongside physical therapy, an optimized lifestyle, and medical monitoring, rather than as a standalone intervention

The metal boot was kept on all times until euthanasia, except during skin inspection, when rats were sedated with isoflurane and the boot was open

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A field guide to ubiquitylation