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3.1 Lactobacillus and Lactococcus species: therapeutic profile The genera Lactobacillus and Lactococcus are cornerstones of probiotic research, characterized by diverse physiological traits and broad-spectrum clinical applications ( Table 2 )

Although the exact mechanism(s) remains unclear, these effects, like that seen in the rat STZ model, have been postulated to arise from improvements in pancreatic insulin synthesis/secretion

J., & Queipo-Ortuo M

Using these two models we search for genes involved in vascular morphogenesis and ask funtional/mechanistic questions using genetics (transgenics and knock-outs in the case of the mouse) and molecular biology (transfection or chicken embryos using electroporation)

Studies have found that females with PCOS have a threefold increased risk of developing GDM compared to those without PCOS, with a significantly higher risk for women with the hyperandrogenic PCOS phenotype (Yan et al., 2022)