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In bladder cancer cells, the poor permeability of Asp cells prevents the uptake of Asp by tumor cells from the environment

In addition, the concentration of 5MTHF in the CSF is lower than normal in patients with idiopathic cerebral folate deficiency, and some patients also have reduced concentrations of CSF 5-hydroxyindoleacetic acid and biopterin

Based on this approach, the same lab also reconstituted the biosynthesis of noscapine ( 95 ) (Figure 44), a pthalideisoquinoline alkaloid isolated for centuries from the native Papaver somniferum plant, at mg/L titers

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Pharmacological rescue of carnitine transport in primary carnitine deficiency