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The adverse impact of maternal smoking on health outcomes in the next generation has been well studied, including increased risk of type 2 diabetes mellitus, impaired renal function and structure, and sudden infant death (Jaakkola and Gissler, 2004

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Also, NADPH is needed for fighting against oxidative stress 3

In experimental and clinical studies, some drugs targeting metabolic pathways have demonstrated promising therapeutic effects, such as anti-inflammatory, anti-oxidative, and tissue repair promotion

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