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This antioxidant also appears to suppress the deleterious effects of other pro-oxidant agents such as oxidized low-density lipoprotein (Ox-LDL) and hydrogen peroxide (H 2 O 2 ) on collagen type X expression, which is linked to hypertrophy-like changes in chondrocytes

doi: 10.1074/jbc.RA118.005953

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Oyama T, Miyasita Y, Watanabe H, Shirai K

Notably, EGCG reduces the accumulation of MDSCs by inhibiting the secretion of cytokines such as inducible nitric oxide synthase (iNOS), Nox2, NF- B, and STAT3