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Description
ADAD is caused by rare and fully penetrant mutations in one of the three genes, APP and presenilin (PSEN) 1 and 2 , which follow a Mendelian autosomal dominant inheritance pattern

Kombat E, Bonu-Ire M, Adetunde L, Owusu-Frimpong M

Nonetheless, the precise mechanistic underpinnings remain elusive, and as of yet, clinical trials focusing on NNMT have not been documented
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