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Vitamin B12 is unique in that it is almost exclusively found naturally in foods derived from animals

The numbers below come from two places: rodent studies scaled to a human size (allometric scaling) and several years of research community use reports

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Microbial contamination: The microbial limit should be continuously monitored during the shelf life to ensure the product is sterile

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Rather than directly supplying NAD+ precursors (like NMN or NR), it works by blocking an enzyme that consumes nicotinamide, theoretically preserving the substrate pool for endogenous NAD+ production