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Biographical Memoirs of Deceased Fellows

For example, the vaccine candidate MalariVax was produced by inserting CSP T-epitopes at the C-terminus of truncated HBc and the T1/B repeat epitopes into the MIR loop (Pumpens et al., 2002), and HPV L1 VLPs can successfully assemble with up to 60 amino acids of HPV-16 E7 fused to the L1 C-terminus ( From a manufacturing standpoint, although genetic fusion utilizes a simplified single-expression system, fusion constructs frequently require extensive, antigen-specific optimization because large or structurally complex antigens often express as insoluble aggregates or inclusion bodies, as exemplified by HBc fusions with SARS-CoV-2 RBD in which only low yields of soluble VLP were obtained without scaffold modification (Petrovskis et al., 2024)

Researchers designed Adipotide to target the vasculature supporting white adipose tissue rather than the fat cells themselves

MiR-15a/16 deficiency enhances anti-tumor immunity of glioma-infiltrating CD8+T cells through targeting mTOR

If you present to your GP with recurrent mouth ulcers and other suggestive symptoms, a systematic diagnostic approach will be undertaken

Endotoxin can compromise cell-culture and other sensitive research, and many vendors skip it