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Although this pregnancy rate is lower than with in vitro fertilization and intracytoplasmic sperm injection, intrauterine insemination is often recommended first when feasible due to its lower invasiveness and cost

In contrast, the mildest form, type C, involves mild and intermittent lactic acidosis with normal (or slightly delayed) development and standard life expectancy [4953]

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OS-induced protein oxidation following cryopreservation can reduce cellular enzyme efficiency, lower ROS-scavaging potential, and ultimately cause cell damage, particularly in sperm cells due to lack of their antioxidant systems to protect against oxidative injuries (7276)

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