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Non-KCN DEGs in Multiple E1E70 Studies In E1E70, the most frequent non-KCN DEGs found were ITGA2, HMGA2 , LIF , and PLAUR , with each found in six to seven studies

Oxidative cell death in tumor therapy ROS play dual roles in tumor development [183,184,185]

GLS, one of the key enzymes in this pathway, is upregulated in various tumors and is thus considered a potential therapeutic target for cancer

The first one is hyperglutamate theory, which accepts that glutamate levels are high in the serum and plasma of individuals with ASD, and the second one is the hypoglutamate theory, which states that there is dysfunction in glutamate receptors in ASD and glutamatergic agonists may have a positive effect on some of ASD symptoms [55]

J Ethnopharmacol 289:114920