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Cognitive and Neurological Research Cognitive and neurological research in 28-month-old mice using 10 mg/kg body weight 5x per week for 3 weeks showed significantly faster escape hole finding in Box Maze tests with evidence of decreased brain inflammation and increased histone deacetylase 2 labeling

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Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1