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[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Wiese G.N., Biruete A., Moorthi R.N., Moe S.M., Lindemann S.R., Gallant K.M.H
It has been shown to improve cognitive function, reduce neuropathic pain, and slow the progression of Alzheimer's disease
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13-15 While early studies highlighted the cntA/cntB oxygen-dependent monooxygenase system as a key route for L-carnitine metabolism, more recent evidence indicates that the anaerobic -butyrobetaine utilization (gbu/bbu) pathway is the dominant contributor under physiological gut conditions
The allopurinol challenge test is an alternative method for diagnosing OTC deficiency when it isnt clear from the lab studies
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