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2.2.2 Key driving factors 2.2.2.1 Iron overaccumulation The core driving factor of ferroptosis is the excessive accumulation of iron, and this process is mainly regulated by iron homeostasis regulators such as transferrin receptor (TFR), ferritin, and ferroportin (FPN) (Zhang et al., 2025c)

This allows for more frequent, high-quality training sessions and reduces the risk of overtraining

[DOI] [PubMed] [Google Scholar] 272.Bezzerides A.L., McGraw K.J., Parker R.S., Husseini J

Cellular redox: A modulator of intestinal epithelial cell proliferation

The reductions were statistically significantly greaterthan those receiving placebo at two sites, namely the right side of the face and the sun-exposed left forearm (p-values = 0.021and 0.036, respectively)

It is commonly used in endocrinology research, molecular biology, receptor pharmacology, and peptide signaling studies
