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10.1534/genetics.115.179457 Genetics 138 McIntoshT.NobleL.AndrewsB.FadenA

doi: 10.1038/s41586-022-05213-y 62 HoffmannJFichtnerILemmMLienauPHess-StumppHRotgeriAet al

B12 is required for converting food into usable cellular energy

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In 1997, Lee published a groundbreaking paper in the New England Journal of Medicine showing that acetaminophen was the leading cause of acute liver failure at Parkland Memorial hospital in Dallas, despite the drugs apparent overall safety. Not to be confused with chronic liver failure, such as that caused by alcoholism, acute liver failure is a sudden, often fatal condition that affects about 2,000 Americans each year