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Figure 3 Figure 4 Cellular insults, including oxidative damage, cause erythrocytes to be marked for removal from circulation

DDR, DNA Damage Response

Pitt JJ, Brown GK, Clift V, Christodoulou J

Host defence against disseminated Candida albicans infection and implications for antifungal immunotherapy

The clinical effects of these disorders depends on the severity of enzyme deficiency and whether the -glutamyl cycle also is affected in non-erythroid tissues

Its role in regulating the sleep cycle is not so straightforward
