how to get rid of melanotic macule Brown spots, especially on the lips, can be alarming some. In some instances it can indicate rare oral mucosal melanoma, however in this case it was a non-cancerous labial macule. Mucosal melanocytic macules

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Talmud PJ, Cooper JA, Hattori H, Miller IP, Miller GJ, Humphries SE

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A conserved region termed the sterol-sensing domain, which consists of 180 amino acids and five transmembrane segments capable of binding sterol groups, is present in many membrane proteins, including several that take part in cellular cholesterol homeostasis or trafficking

Morphologically, the tumor was consisted of two types of cells which arranged in irregular alveolar, tubuloglandular and fissured architecture, with cords and strands intersected by dense fibroblastic stroma ( Figure 2 )