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(Full disclosure: I initially miscalculated, or, more accurately, I completely borked the math

Specifically, 5-amino-1MQ and 7-amino-1MQ exhibited high passive and active transport across membrane, with no detectable efflux observed in the Caco-2 cell assay

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Although cutoffs around 3545 pmol/L are often used in clinical practice and in research, in a large clinical study there was no association between holoTC and MMA in the range of 2550 pmol/L (243)