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Their group also revealed that 9-ING-41 significantly enhanced 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) antitumor activity in chemo-resistant PDX models of GBM by decreasing tumor size and increasing overall survival (119)

Luciferin is quantified using Ultra-Glo Recombinant Luciferase, which is a component of the Luciferin Detection Reagent, and the light signal produced is proportional to the amount of NAD+ or NADH in the sample

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Lung Radiation-induced lung injury (RILI) is a prevalent and potentially fatal off-target effect of thoracic radiotherapy, with limited effective interventions available [56, 69, 70]
