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doi: 10.1016/0003-4975(96)00055-0 169 QinCLiuRGuJLiYQianHShiYet al
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Clinically proved to moisturize skin for 24 hours and protect from dryness
Using flies and mice, it has been demonstrated that sleep deprivation results in the accumulation of ROS with consequent oxidative stress in the gut, rather than in the brain (Vaccaro et al
Our findings are in line with other reports showing a decrease in Sirt6 protein expression in transgenic mice (5XFAD) 133 as well as decreased gene and protein expression in AD patients 133,134

Interestingly, finasteride also inhibits the activity of steroid 5-reductase, a soluble steroid reductase that belongs to the NADPH-dependent aldo-keto reductase (AKR) superfamily 43
