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Immunofluorescence showed that rhCOL17A1 upregulated its own expression while slightly decreasing MMP-9 expression in hDPCs
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In addition, interventions that inactivated neutrophils independent of neutropenia such as CD18 antibodies116, inhibitors of NADPH oxidase117, and use of mice deficient in CD1894, intercellular adhesion molecule-1117, or NADPH oxidase118 all were not protective against APAP-induced liver injury
