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The yeast prion protein Sup35 initiates -synuclein pathology in mouse models of Parkinson's disease
Therefore, targeted therapeutics that block this oncogenic pathway, including BRAF and mitogen-activated protein kinase (MEK) inhibitors (BRAFi and MEKi, respectively), are widely used to treat metastatic melanoma 6
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Approximately 70% of GPX3, the predominant form in the basolateral compartment of kidney cells [15], is secreted by the basolateral membrane of proximal convoluted tubule cells [16]
Pharmacol Ther 234:108117 Apostolova N, Gomez-Sucerquia LJ, Moran A, Alvarez A, Blas-Garcia A, Esplugues J (2010) Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells
