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In alignment with the minimal information for studies of extracellular vesicles (MISEV) 2024 guidelines 31 , we further performed in-depth characterizations of off-gel recovered EVs and compared them with established methods using various analytical techniques (Supplementary Results), including nanoparticle tracking analysis (Extended Data Fig

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Generative AI statement The author(s) declared that generative AI was used in the creation of this manuscript

This treatment restores essential NAD+ levels in your cells, promoting energy production, brain health, and overall recovery