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In addition, complications related to vascular access, such as catheter sepsis and thrombosis of arteriovenous fistulae, favor inflammation [28,31,32]

Its use has an impact on the gut microbiota, causing significant alterations in microbial diversity and metabolic pathways that can have far-reaching consequences for overall health

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The activation of innate and adaptive immunity involves CD80

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Concurrently, leucine, which is categorized as a branched-chain amino acid, serves as a powerful activator of the mechanistic target of rapamycin complex 1 (mTORC1) signaling pathway, thereby promoting MPS and mitigating the effects of muscle atrophy (12, 13)