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Macrophages also exist in a resting or activated state, with activated macrophages further divided into M1 (so-called classical or inflammatory macrophages) and M2 (aka alternative or reparative) subtypes

Deletion of the Src gene and inhibition of Src kinase activity markedly suppress JNK activation in the ROS-mediated JNK signaling pathway, with no discernible impact on ERK and p38 activation (46)

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Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production