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The chemical reactivities of iron and sulfur, together with variations in the composition, redox potential, oxidation state, physical accessibility of the cluster and effects of the local protein environment, enable these versatile cofactors to accept or donate single electrons, catalyze enzymatic reactions or function as regulatory proteins

IL-17 also counters intestinal inflammation by downregulating chemokines involved in CD8 + cytotoxic T cell recruitment and upregulating immunoregulatory M2 macrophages [115, 117]

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The mixture is then passed through a fresh glutathione resin column to remove the cleaved GST tag, allowing the purified target protein to be collected in the flow-through

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