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Macrophages and dendritic cells produce IL-1 through macro-molecular complexes called inflammasomes, including the major element present in the pulmonary tissue and the nucleotide-binding oligomerization domain (NOD)-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome [20]

2018;49:113247.e1137

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doi:10.1016/b978-0-12-815849-4.00001-3

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Specifically, tumor cells maintain moderate-to-high ROS levels, namely, above the low cytostatic level and below the cytotoxic level, by enhancing their own antioxidant capacity