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This condition arises from various lifestyle or disease conditions such as chronic hyperglycemia or ketoacidosis attacks, excessive nutrient intake, and sleep disorders [19]

Phosphorylation of smooth muscle 22 facilitates angiotensin II-induced ROS production via activation of the PKC-P47phox axis through release of PKC and actin dynamics and is associated with hypertrophy and hyperplasia of vascular smooth muscle cells in vitro and in vivo

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