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Pediatr Nephrol 18 : 207215 Baum M 1998 The Fanconi syndrome in cystinosis: insights into the physiopathology

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First, ROS directly modifies ion channels, oxidizing sulfhydryl groups on voltage-gated Na+ channels, resulting in abnormal action potential propagation and contributing to the paradoxical coexistence of pain and numbness (Elafros et al., 2022)

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Around Week 12: Body Composition The twelve-week mark is when measurable changes in body composition typically emerge: increased lean muscle mass, a decrease in visceral fat, and visible changes to waist circumference and overall shape

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