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Inhibiting ZDHHC18 or mutating HRAS palmitoylation sites alleviates fibrosis (Lu et al., 2025)

Therefore, additional research is imperative to unravel the precise mechanisms governing cell death induced by copper (Tsvetkov et al., 2022)

10.1038/s41467-020-15156-5 Nat

[DOI] [PMC free article] [PubMed] [Google Scholar] [87].Zhang Y, Swanda RV, Nie L, et al

Figure 4 5.10 Summary of ferroptosis-targeted therapeutic strategies Based on the disease-specific discussions above, ferroptosis-targeted therapeutic strategies can be categorized into three main approaches based on their mechanisms of action: Iron Chelators (e.g., Deferoxamine, Deferiprone) sequester labile iron to limit Fenton chemistry-driven hydroxyl radical generation

Mitochondria as a target for mitigating sarcopenia
