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Third, current evaluations of interventions such as copper chelators, metal-protein-attenuating compounds (MPACs), and gene therapy remain constrained by dosage windows, blood-brain barrier permeability, and individual variability, necessitating large-scale clinical trials to confirm their safety and efficacy

discovered that flavonoids prevented atherosclerosis and reduced LDL oxidation [207]

Impact of duration of untreated psychosis and premorbid intelligence on cognitive functioning in patients with first-episode schizophrenia
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& Liu, S.-L
