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Placing CM-7 in this reasonable outline underlines two significances: (i) standardized in vitro digestion and ex vivo/clinical bioavailability models to benchmark physiological applications

One biological replicate is represented by a single fly, unless otherwise specified

These observations underscore the involvement of the hypoxic microenvironment in MS-associated vascular pathology, implying that strategies aimed at improving vascular oxygenation, mitigating immunoinflammatory damage, downregulating vasoactive substances, and reversing vascular abnormalities may reduce ischemic damage to the skin and visceral organs

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For example, a total of 169 women of childbearing age were evaluated, comprising 76 who received CoQ10 treatment and 93 in the control group