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Although this fact did not seem overly significant in 1890, when Tucson still held the lead over Phoenix in population and prosperity, during the subsequent period, in which calls for federal reclamation appeared, the potential usefulness of the Salt River became pivotal

Critically, the study documented no significant changes in oral glucose tolerance tests, no alterations in fasting insulin levels, and no changes in serum IGF-1 concentrations across all treatment groups

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contributed to the investigation, establishing methodology, and writing the original draft of the manuscript

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