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In the elderly, hypothyroidism is associated with accelerated cognitive decline and an increased risk of Alzheimer's disease, raising the possibility that impaired thyroid signaling may act as a modifiable risk factor for dementia (83)

doi: 10.1038/nrm.2017.53

Matrixyl produces no comparable genomic effects

These little inhibitors help prevent the development of excessive amounts of melanin

Thus, there is evidence to show that it has a role in helping depression and stress, as well as emotional and cognitive function