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The expression levels were compared between treated and control groups [2]

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Normal fibroblasts acquire the CAF phenotype and secrete many cytokines and oncogenic ECM that contribute to tumor growth and metastasis

The release and excessive accumulation of collagen fibers caused by overactivated fibroblasts, which are marked with fibroblast activation protein (FAP), lead to pathological changes in the extracellular matrix (ECM) and persistent inflammation, resulting in a vicious cycle of cellular activity and extracellular fibrosis 3,4,5,6,7

Non-animal sources include fortified or enriched milk substitutes, grains, and nutritional yeast

doi: 10.1093/oxfordjournals.bmb.a072641