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The peptide downregulates TNF- (6.2-fold reduction) and IL-6 (4.1-fold reduction) while upregulating anti-inflammatory IL-10 (8.1-fold increase)[12]

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DSIP: Short for delta sleep-inducing peptide, DSIP is discussed for sleep, recovery, and stress regulation

Even Avecho Biotechnology (formerly Phosphagenics), a company who wanted to repurposed AOD-9604 as a transdermal formulation, knew why the clinical trials failed: AOD9604s delivery could have been the key issue

Intranasal administration of cyanocobalamin gel is an option for vitamin B12-decient patients who are sensitive to benzyl alcohol