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In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected

doi: 10.3389/fimmu.2022.943241 230 ParodiENoviMBottinoPLa PortaEMerlottiGCastelloLMet al

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Sheep & Goat: 24 ml per animal for 45 days

Proc Natl Acad Sci USA 83:76587662 Trovato M, Mattioli R, Costantino P (2008) Multiple roles of proline in plant stress tolerance and development
