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Glutamine reduces postprandial glycemia and augments the glucagon-like peptide-1 response in type 2 diabetes patients

Immune cells, such as T-cells and Natural Killer cells, require adequate glutathione to multiply and respond to challenges effectively

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The disruption of inter-organ communication due to AT dysfunction accelerates the aging process and increases metabolic disease risk (426)

The response to linsitinib is inferior to the topoisomerase inhibitor topotecan, with median progression-free survival of 3.0 (95% CI 1.53.6) and 1.2 (95% CI 1.11.4) months for topotecan and linsitinib, respectively [159]

Evidence suggests that hypoxia induces the overexpression of diacylglycerol kinase (DGKG) in tumor endothelial cells, which then activates the ZEB2/TGF-1 axis, promoting angiogenesis and immune suppression in HCC