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In vitro signaling profiles and propensities for receptor desensitization of two clinically studied FPR2 agonists, namely, BMS-986235 and ACT-389949, were evaluated

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Mast cellsare immune cells that help trigger allergy symptoms by releasing histamine and other signaling compounds. Histamineis one of the substances most associated with itching, swelling, watery eyes, sneezing, and congestion