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Additionally, a large GWAS in ME/CFS is desperately needed to assess the biomolecular mechanisms of ME/CFS (56)

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Rat studies have noted embryofetal mortality, structural abnormalities, and alterations to growth at maternal exposures below the maximum recommended human dose (MRHD) based on exposure AUC

This study aimed to determine the safety and pharmacokinetic profile of the BPC 157 peptide (NCT02637284) [105]

Split dosing: Some practitioners split the daily dose into 250 mcg AM and 250 mcg pre-sleep on the rationale that two smaller pulses maintain steadier receptor exposure