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Inform patients of the risk of life-threatening respiratory depression, including information that the risk is greatest when starting hydrocodone bitartrate and acetaminophen tablets or when the dosage is increased, and that it can occur even at recommended dosages

Cui L-B, Wang X-Y, Fu Y-F, Liu X-F, Wei Y, Zhao S-W, et al

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Although myelin may be seen in some invertebrates such as crustaceans, the vertebrate CNS myelin is a sui generis phenomenon among animals as its morphology and cell origin are unique to that clade ( The particularities of myelination in CNS are not restricted to myelin itself, though

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Notably, upregulation of serpinA3N was found in AD model mice (Han et al., 2024)