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Rupture of the Spleen should be considered in rare cases of chronic hemolytic anemia Chronic Hemolytic Anemia Anemia: Overview and Types

Third, given their reliance on lipid metabolism, B1 and MZB cells are extremely susceptible to lipid peroxidation and subsequent ferroptosis secondary to ROS accumulation 142

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(PubMed) Zhou Y, Sinnathamby V, Yu Y, et al