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Matt Cook leads a team of six MDs with over 20 years of collective regenerative medicine experience

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It has been shown that EVs derived from CRC can alter the TME, leading to tumor development and spread by promoting immune evasion and a cancerous phenotype in recipient cells (Figure 3) (Glass and Coffey, 2022)

doi: 10.1210/en.2010-1464 95 LiZLiuQLiCZongXBaiJWuYet al

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We show that exosomal GRP affects pathogen acquisition and transmission, exosome biogenesis, and modulates host immune evasion via regulating human chemokine CXCL-12