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Targeted inhibition of gut microbial trimethylamine N-oxide production reduces renal tubulointerstitial fibrosis and functional impairment in a murine model of chronic kidney disease

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de Alencar JCG, Moreira CL, Mller AD, Chaves CE, Fukuhara MA, da Silva EA, Miyamoto MFS, Pinto VB, Bueno CG, Neto FL, Gomez LM, Menezes MCS, Marchini JFM, Marino LO, Brando Neto RA, Souza HP (2021) Double-blind, randomized, placebo-controlled trial with N-acetylcysteine for treatment of severe acute respiratory syndrome caused by Coronavirus disease 2019 (COVID-19)