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doi: 10.1016/s0022-3476(67)80019-2

found that intratracheal instillation of NiO NPs increased levels of pro-inflammatory cytokines, neutrophil and proteins in the bronchoalveolar lavage fluid (BALF) and triggered apoptosis and iron-deficiency in the lung tissue

Nanoencapsulation of betamethasone valerate using high pressure homogenization-solvent evaporation technique: optimization of formulation and process parameters for efficient dermal targeting

This concentrated delivery system is crucial for therapeutic use, as achieving clinical doses through diet alone is often impractical, especially for patients with gastrointestinal sensitivities or histamine intolerance who may struggle to digest large volumes of raw broccoli

A oligomer toxicity studies in primary cortical neuron cultures further supported these findings