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Five Peptides Every Endurance Athlete Should UnderstandFrom Mitochondrial Signaling to Connective-Tissue Remodelingand How AI Helps By Tony Medrano | CEO & Co-Founder | LongevityPlan.AI | March 2026 Introduction: Why Peptides Are the New Frontier for Endurance Athletes In the spring of 2015, a small laboratory at the USC Leonard Davis School of Gerontology announced something that made exercise physiologists sit up straight: a sixteen-amino-acid molecule encoded not in our familiar nuclear DNA but in our mitochondrial genome could, when injected into obese mice, replicate many metabolic benefits of exercisesuppressing weight gain, reversing insulin resistance, and boosting endurance.1 The molecule was called MOTS-c, and its discoverersChanghan David Lee and Pinchas Cohenhad effectively opened a door that the endurance community has been walking through ever since

[25] Consider [26] Rootcologys Selenium + Myo-Inositol , which contains clinically studied doses of each nutrient to support optimal thyroid function.* You can read more about addressing [27] selenium deficiencies in my article

If you've been running on empty for a while with severe deficiencies, you might need a few sessions before experiencing dramatic improvement

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Rhodiola is an herb that has been used for centuries by those in regions of Asia to help manage stress and fatigue

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