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AOD 9604 meets the first two criteria clearly

Oral vitamin B12 without intrinsic factor in the treatment of pernicious anemia
Retatrutide handles the heavy lifting on appetite and metabolism, while AOD-9604 fills a gap that no incretin-based peptide can address: direct, receptor-level stimulation of fat breakdown
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Human trials have shown modest but consistent fat reduction, particularly when combined with proper diet and exercise
