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These ketocarotenoids were initially believed to indicate individual maturity and be involved in defense against oxidative stress and regulation of immunity

The results showed that sustained exposure to Ni NPs led to a significant inflammatory response in the liver, upregulation of ER stress sensors such as inositol-requiring enzyme 1 (IRE1), pancreatic ER kinase (PERK), and ATF6, and activation of apoptosis in liver cells

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For short-term storage prior to reconstitution, refrigeration at 2-8C is acceptable for a few weeks

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