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RS, with an incidence of 1:10,00015,000, is the second most common cause of severe intellectual disability in women, and during its developmental regression, a substantial proportion of patients meet the diagnostic criteria for autism spectrum disorder (ASD) [77,78,79,80,81,82,83]

This dual-action approach optimizes the entire ATP production pathway, ensuring that the mitochondria have both the raw materials and the transport infrastructure necessary to maintain high levels of energy output, which is particularly crucial for patients suffering from chronic energy deficits

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