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But Increased GH and IGF-1 Are Not a Free Upgrade Endocrine changes at this scale come with potential trade-offs: Fluid retention Glucose regulation concerns Possible long-term diseases questions linked to IGF-1 elevation (Holt, 2025

57% had stable or improved EDSS scores (change 0.5 or fewer points)
b) acute alcohol exposure promotes activation of D1 SPN

And while reverse osmosis filtration will also remove any minerals present, other purification processes like boiling and deionization will not
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Carcinogenesis, 5: 231-243
